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Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
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Description
FOLATE-5 PLUS (120T) *Folate 5 Plus supplies calcium folinate, along with vitamin B12 and the antioxidant enzymes SOD and catalase. This high potency folate product is appropriate when significant supplemental folic acid is warranted. Adequate folic acid levels may reduce a woman's risk of having a child with neural tube defects. Folate has other beneficial actions as well. For example, adequate folate status is correlated to the expression of proteins involved in the
Folate-5 Plus™ supplies calcium folinate, along with vitamin B12 and the antioxidant enzymes SOD and catalase. This high potency folate product is appropriate when significant supplemental folic acid is warranted. Adequate folic acid levels may reduce a woman's risk of having a child with neural tube defects. Folate has other beneficial actions as well. For example, adequate folate status is correlated to the expression of proteins involved in the activation and regulation of immune function. The synthesis of the neurotransmitters dopamine, epinephrine and serotonin also require folate as a cofactor. Folate deficiency may also result in reduced DNA methylation, which can cause chromosomal instability and increase mutation events. Folic acid is also important in maintaining healthy homocysteine levels.
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Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.8 ★★★★★
Based on 1002 reviews
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Product Reviews
★★★★★ 5
Sturdy and long lasting.
These balls are a favorite of my Sheltie! She loves to chase after them and catch them in the air. My dog is not a chewer so I can't say how they hold up under aggressive circumstances! They do last a long time .
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Reviewed in the United States on August 3, 2025
★★★★★ 5
Dog loves this ball
Our dog loves it!
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Reviewed in the United States on April 15, 2026
★★★★★ 5
Dog is in love with this Toy!
Color: Assorted, Size: Medium
This is a super great dog toy & one of the best we have purchased for miss "destroy the toy" dog! I have an Australian Cattle Dog who has a pretty big chomp reflex. She destroys most all of her ball toys in just a few minutes because she chomps so hard. So far, this is the only "open type" of dog ball toy she has not ruined quickly. It's actually lasted over a year so far! It is showing some wear & tear & a couple ares have almost been chomped through, but that would be expected with the way she chomps on it. She absolutely adores this toy & it is her total favorite! It has been well worth the money & then some for her. I've already bought a couple of "spares" but she is still playing with the original one I bought. Please note: I never, ever leave it alone with her! I use it only to throw or kick & for her to chase & retrieve. I try not to let her just chew & chomp on it, but that is what she'd really like to do. We play with it all year long, even in the snow. It's fun in winter because it does not sink & get lost in deep snow as quickly as a tennis ball sized toy would. It fills up a bit with snow, but that seems to make it even more fun for my dog. I highly recommend this toy. I just wish JW would offer it in some other brighter colors besides the blue.
01/06/2016 Update:
My dog still is playing with this very same Hol-ee Roller X Extreme! I'd bought her a couple of spares but this 1st one is still holding up under her chompers! It's worn looking but has not torn or broke yet. I do not let her just sit and chomp on it though. It used as a retrieving and chasing toy, but she does get a few goods chomps in each time she gets it. We play with this toy basically every single day, so I'd say this is a very durable dog toy and the best one I have bought ! I highly recommend it.
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Reviewed in the United States on January 19, 2015
★★★★★ 5
A Giggling Good Time for My Furry Friend!
Color: Red, Size: Medium
My dog absolutely loves the JW Pet Hol-ee Giggler Dog Toy Puzzle Ball! Here's why I think it's a great choice:
Pros:
Engaging Giggle: The giggle sound is so unpredictable and fun that it truly keeps my dog entertained. He goes nuts chasing it around and trying to figure out how to make it giggle more.
Durable Rubber: This toy has held up surprisingly well to some intense chewing and playing. The natural rubber is tough but still gentle on his teeth.
Versatile: It's more than just a noisemaker! It's great for fetch, and I can even stuff it with treats to turn it into a puzzle toy.
Cons:
Giggle Mechanism: The giggle tube inside can be a little delicate. If your dog is a super aggressive chewer, they might be able to dismantle it.
Not for Quiet Time: If you want a silent toy, this isn't it! The giggle can be quite loud when your dog is really going at it.
Overall:
I would definitely recommend the JW Pet Hol-ee Giggler to other dog owners. It's a fun, durable, and unique toy that provides a lot of stimulation for pups. Just be aware of the potential for the giggling mechanism to break under heavy chewing, and be prepared for some added noise!
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Reviewed in the United States on January 29, 2024
★★★★★ 5
DIEGO'S FAVORITE OUTSIDE BALL!
Color: Assorted, Size: Medium
JW PET COMPANY HOL-EE ROLLER EXTREME
This is the second HOL-EE ROLLER ball we have purchased for our Diego. He LOVES these! He now owns a black one and a blue one. He loves to toss these around the yard all by himself or have us throw them to him. He looks so adorable when he comes running back to us, with the HOL-EE ROLLER in his mouth and he has the sweetest expression on his face and is so happy he is prancing! He is a rescue Pit mix from PR. He survived Hurricane Maria and was there before, during, and after. If he could only tell us his tale.
The ball is sturdy. The honey comb design gives your baby the ability to grasp and hold the ball. Diego also likes to hold the ball down and gnaw on it. The ball has proven to be safe against his little vampire teeth. The blue ball was in our yard the entire winter during every type of element you can think of. It is is great shape. Diego plays with these balls constantly while outside. They are sturdy and he is able to get a nice grip on them. These balls are tested by the company to make certain they do not contain any harmful chemicals. The ball has plenty of bounce to it too!
The balls come in different colors but which color you receive will be a surprise.
JW products are AWESOME. Diego also has a trio of smaller indoor balls that he has had for three years now. They are still like brand new. He loves to play with these. They have grips on the outside for him to try to chew on, but he can't destroy them.
JW has other types of pet toys and products available for you. Check them out. Your dog will thank you.
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Reviewed in the United States on June 29, 2020
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