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Description
Arginase-1 Recombinant Rabbit mAb,PBS Only (SDT-369-33)Product Specification Host Rabbit Antigen Arginase 1 Synonyms Liver type arginase; Type I arginase; ARG 1 Location Cytoplasm Accession P05089 Clone Number SDT 369 33 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IP Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4 C as supplied
Product Specification
| Host | Rabbit |
| Antigen | Arginase-1 |
| Synonyms | Liver-type arginase; Type I arginase; ARG-1 |
| Location | Cytoplasm |
| Accession | P05089 |
| Clone Number | SDT-369-33 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | |
| IP | 1:25 | |
| IHC | 1:1000 | |
| ICC | 1:50 |
Background
Arginase belongs to the urea hydrolase family of enzymes. It's one of the key enzymes in the urea nitrogen cycle and catalyzes the fifth and final step in the urea cycle, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. Specifically, arginase converts L-arginine into L-ornithine and urea. It was found to be highly specific in normal liver cells, but not in bile duct epithelial cells, hepatic sinus endothelial cells, vascular endothelial cells, and Kupffer cells. It is a specific and sensitive marker for hepatocellular adenoma and hepatocellular carcinoma (more sensitive and specific than HepPar1 and Glypican-3).
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